Portage (OTC: $PTGEF) Advances Immuno-Oncology Company into its Second Drug Candidate


The IBR radar goes off yet again in the light of new positive developments in the biotech space, following news announcements from Portage Biotech Inc. (OTC: $PTGEF).

iOx Therapeutics, Ltd. (“iOx”) is a spin-out from the University of Oxford starting to commercialize discoveries made as part of a long-running collaboration between Oxford and the Ludwig Institute for Cancer Research.

Preliminary research indicates that the synthetic lipid compounds, iOx intends to develop and commercialize, activate invariant natural killer T-cells (iNKT cells), which, a large body of evidence suggests, play an important role in anti-tumor immune responses.

Further developments in the oncological treatment are huge wins in the fight against cancer and also of great significance for Portage Biotech Inc.

Portage will invest a further $950,000 US in iOx Therapeutics by subscribing to an unsecured, convertible loan instrument.

Note: The current market cap of Portage is $125M +-. We see Portage trading up around the .40 cent range in 2020 from a current .11 representing a possible 4X return.



Here is the latest press release dated January 30, 2020

Portage Announces Further Subscription of US$950,000 in Convertible Loan Notes to iOx Therapeutics and Provides Update on CTO Revocation Application

TORONTO, Jan. 30, 2020 /PRNewswire/ – Portage Biotech Inc. (PBT.U, OTC Markets: PTGEF) (“Portage” or the “Company”) is pleased to announce that it has increased its subscription to iOx’s convertible loan to $2.9M USD, (previous subscriptions totalled $1.9M on December 8th, 2018).

iOx Therapeutics, Ltd. (“iOx”) is a United Kingdom-based immuno-oncology company.  Portage will invest $950,000 by subscribing to an unsecured, convertible loan instrument.  iOx will use the proceeds to enable the start of human studies this year.  The notes carry a 7% interest rate and will price at a discount to the next round of financing into iOx. The terms of the notes differ from those announced previously as these carry two year warrants to purchase additional shares at the same price as the next financing.  All three convertible notes currently held by Portage have been extended.

Greg Bailey, Chairman of Portage, remarked, “We are looking forward to iOx achieving a major milestone and begin to collect safety data in cancer patients.  This bridge financing will support the iOx team to advance this asset as well as to continue to support the PRECIOUS consortium in Europe who has received Horizon 2020 funding to advance its second drug candidate into the clinic.”

Related Party Transaction

The transaction is a related party transaction within the meaning of Multilateral Instrument 61-101 Protection of Minority Shareholders in Special Transactions (“MI 61-101”) as Portage’s CEO, Dr. Ian B. Walters serves as iOx’s CEO and Dr. Declan Doogan, a director of Portage, is iOx’s chairman. The transaction, however, is exempt from both formal valuation and minority shareholder approval requirements under MI 61-101. The Company has relied on exemptions from the formal valuation and minority shareholder approval requirements of MI 61‑101 contained in sections 5.5(a), 5.5(b) and 5.7(1)(a) of MI 61‑101 in respect of related party participation in this transaction as neither the fair market value (as determined under MI 61-101) of the subject matter of, nor the fair market value of the consideration for, the transaction, insofar as it involved the related parties, exceeded 25% of the Company’s market capitalization (as determined under MI 61-101).

Corporate Update

The Company is also providing an update on the status of its application (the “Revocation Application”) to the Ontario Securities Commission (the “OSC”) to revoke an outstanding cease trade order issued on August 2, 2019 (the “CTO”).

The OSC has commenced their review of the Revocation Application (filed on January 13, 2020) and issued an initial set of comments. The Company is currently preparing a response which is expected to be submitted shortly. As the relief being sought is discretionary, no estimate can be provided as to when a revocation order may be issued by the OSC. The Company, though, would like to take this opportunity to thank its shareholders for their continued patience. It is the Company’s every intention to complete the OSC’s review process in a timely manner.

Luka Marjanovic


Luka holds a Bachelor’s in International Business and a Master’s in International Management. During his undergraduate studies he worked as a research assistant in the field of Big Data; founded his own consulting firm providing services to local SME's in various sectors and invested in the capital markets; as well as working pro-bono providing education and career counselling. Prior to his business education, he studied Biology-and-Biotechnology, and served in the Danish Royal Army as Second Sergeant, leading and managing a group under extreme conditions and pressure. Luka has spent significant time abroad, living and working in seven different countries. When he's not in the office, he's chasing the next gusts windsurfing, carving the mountain snowboarding or out in the forest for a jog.